The German federal ministry of education and research (BMBF) supports highly innovative companies in developing new technologies. Our project “intraoperative neuromonitoring for identification and monitoring of nerve tissue of the pelvic floor (NeuroNeB)” is supported by the BMBF since May 2017, being acknowledged as one of the research projects with a notably high innovation content.
The methods for neuromonitoring of the pelvic nerves available today are not satisfying for us, that is why we are going to follow a completely new approach. In cooperation with the Medical Center – University of Freiburg (Germany), Medical University of Innsbruck (Austria) and the clinic of Ludwigsburg (Germany) we are working on new recording methods for a significantly more reliable identification of nerve tissue compared to those procedures used today.
Funding Code: 13GW0192
for identification and monitoring of nerve tissue of the pelvic floor (NeuroNeB)
An animal study on pigs, conducted at the Medical Center – University of Freiburg in 2018, showed very good, reproducible results. Nerve branches of the urinary bladder and/or the rectum innervation were localized successfully. Our recording method, which has been filed for patent, wasn’t only working at the rectum but also at the empty urinary bladder. Consequently, the repeated filling of the bladder, which is very time consuming, is no longer necessary. Tissue samples were sent to the Medical University of Innsbruck for a histological examination to verify the results. Antibody tests detected both sympathetic and parasympathetic nerve fibers in those samples. This confirmed our recording results to be correct. The department of clinical functional anatomy of the Medical University of Innsbruck made a very important contribution to this project because of their expertise in combining surgical and anatomical aspects.
What’s next? Beginning in summer 2019 and in cooperation with the clinic of Ludwigsburg we will conduct a clinical trial on patients for general and visceral surgery. Our motivation is to present our first class neuromonitor for pelvic nerves soon.